Family: Thomas Despenser / Constance of York (F9183)
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 | 1st Baron Despenser Edward Despenser (1336-1375) |
 | Elizabeth de Burghersh (1342-1409)
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| Elizabeth Despenser (1362-1408)  |
| Margaret Despenser (1365-1415) |
| 1st Duke of York Edmund of Langley (1341-1402)
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| Isabel de Castilla (1355-1392)
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| 3rd Earl of Cambridge Richard of Conisbrough (1385-1415) |
| Constance of York (1375-1416)
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| Thomas Despenser (1373-1400)
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| Isabel le Despenser (1400-1439) |