Family: 3rd Lord Sempill Robert Sempill / Lady Isabel Hamilton (F11604)
m. 7 Apr 1538
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 | 2nd Lord of Sempill William Sempill (1485-1552)
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 | Baroness Margaret Montgomery (1487-1523)
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| 1st Lord of Sanquhar William Hamilton (1496-1569)
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| Lady Katharine Kennedy of Cassilis (1491-1566)
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| 3rd Lord Sempill Robert Sempill (1501-1573)
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| Lady Isabel Hamilton (1508-1546)
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| Master of Sempill Robert Sempill (1522-1569)  |