Family: Isaac Angelos, Emperor Issakios II / Herina Tornikaina (F3966)
m. 1181
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 | Andronikos Dukas Angelos (1120- ) |
 | Euphrosyne Kastamonitissa (1125- ) |
| Isaac Angelos, Emperor Issakios II (1156- )
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| Herina Tornikaina (1150- ) |
| Irini Maria Angelina, Queen Of Sicily (1184-1208)  |