Family: Patrick Hepburn, 1st Earl of Bothwell / Janet Douglas (F639)
m. 1 Feb 1479
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 | Adam Hepburn, Master-Baron of Hailes  (1435-1479)
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 | Elyne Helen Home (1440-1480) |
| Margaret Hepburn Of Hailes (1456-1542)  |
| Adam Hepburn (1457-1513) |
| James Douglas, 3rd Earl of Angus (1426-1493)
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| Joan Stewart, Countess of Morton (1428-1498)
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| John Douglas, 2nd Earl of Morton (1459-1513) |
| Patrick Hepburn, 1st Earl of Bothwell (1451-1508)
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| Janet Douglas (1461-1490)
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| Jeanette Gertrude Hepburn, Lord Hepburn (1485-1558) |