Family: 1st Earl of Bothwell Patrick Hepburn / Janet Douglas (F658)
m. 1 Feb 1479
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 | Master-Baron of Hailes Adam Hepburn (1435-1479)
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 | Elyne Helen Home (1440-1480) |
| Margaret Hepburn Of Hailes (1456-1542)  |
| Adam Hepburn, of Craggis (1457-1513) |
| 3rd Earl of Angus James Douglas (1426-1493)
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| Countess of Morton Joan Stewart (1428-1498)
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| 2nd Earl of Morton John Douglas (1459-1513) |
| 1st Earl of Bothwell Patrick Hepburn (1451-1508)
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| Janet Douglas (1461-1490)
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| Lord Hepburn Jeanette Gertrude Hepburn (1485-1558) |