Family: William Ruthven, 2nd Lord Ruthven / Jean Hepburne (F11772)
m. Abt 1500
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 | William Ruthven, First Lord Ruthven  (1460-1528)
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 | Isabel Livingston of Saltcoats, Lady  (1440-1510)
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| Alexander Hepburn of Whitsome (1444-1517)
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| Janet Napier (1424-1513)
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| Agnes Hepburn of Whitsome (1480-1549)  |
 | William Ruthven, 2nd Lord Ruthven (1478-1513)
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| Jean Hepburne (1480-1570)
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| William Ruthven, 2nd Lord Sheriff of Perth (1500-1552) |