Family: Thomas Middleton / Isabel Musgrave (F22353)
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 | John Middleton, of Middleton Hall (1377-1434)
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 | Elizabeth Metcalfe (1383- )
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| Richard Musgrave, II (1397-1464)
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| Lady Elizabeth Betham (1398-1464)
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| Eleanor Musgrave (1421-1516)  |
| Thomas Middleton (1400- )
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| Isabel Musgrave (1409-1475)
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| Margaret Middleton (1431-1505) |