Family: 3rd Lord of Seton George Seton, III / Lord Hepburn Jeanette Gertrude Hepburn (F612)
m. 25 Jan 1507
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 | 4th Laird De Seton George De Seton (1449-1508)
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 | Lady Margaret Campbell (1456- )
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| Martha Eliza Seton (1475-1510)  |
| 1st Earl of Bothwell Patrick Hepburn (1451-1508)
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| Janet Douglas (1461-1490)
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| 3rd Lord of Seton George Seton, III (1481-1513)
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| Lord Hepburn Jeanette Gertrude Hepburn (1485-1558)
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| Countess Of Eglinton Marion Seton (1496-1561) |
| 4th Baron Seton George Seton (1508-1549) |